Equipment Model

Rudolph Research Analytical Autopol I (AP 1)

Description

The Rudolph Research Analytical Autopol I (AP 1) is a high-precision digital polarimeter designed to measure the optical rotation of optically active (chiral) compounds. It is commonly used to determine specific rotation, concentration, and mutarotation of substances in pharmaceutical, chemical, and food applications. The instrument offers accurate readings with automatic temperature compensation and multi-wavelength capability in certain configurations.

Lab

CIF Room No: 3154

Institute

Central Analytical Laboratory

Location

CIF Room No: 3154, Birla Institute of Technology & Science, Vidya Vihar, Pilani, Rajasthan 333031, India

• Applications

  • Pharmaceutical Industry: Determination of enantiomeric purity and quality control of chiral drugs.

  • Chemical Research: Study of stereochemistry, chiral synthesis, and conformational analysis.

  • Food & Beverage Industry: Measurement of sugar concentration in solutions (e.g., sucrose, glucose, fructose).

  • Biotechnology: Analysis of optically active biomolecules such as amino acids and sugars.

  • Academic Research: Educational use for demonstrating chirality and optical activity.

  • Quality Control: Routine analysis of raw materials and finished products for optical purity.

• Key Features

  • Accurate measurement of optical rotation, specific rotation, and concentration.

  • Automatic temperature compensation for consistent readings under varying conditions.

  • User-friendly digital display with straightforward operation.

  • Standard wavelength of 589 nm (sodium D-line), with multi-wavelength options available.

  • Compatible with temperature-controlled sample cells and quartz control plates.

• Limitations

  • Limited to optically active (chiral) substances—cannot analyze achiral compounds.

  • Requires clean, bubble-free liquid samples for reliable measurements.

  • High accuracy applications may need calibration with certified standards.

  • Temperature control accessories may be required for precise studies.

  • Not designed for high-throughput or automation without additional modules.